Vice President, Head of Clinical Operations

ModernaMultiple locationsonsite$272k–$490kView the original posting at Moderna ↗

The Role Joining Moderna means advancing mRNA science to transform medicine. Work with exceptional global teams on a broad pipeline and build a career that makes a real difference for patients. Moderna is strengthening its presence in Cambridge, Massachusetts, home to our global headquarters and a center of mRNA innovation. Working closely with leading universities and research institutions, our Cambridge team advances groundbreaking science that shapes the future of medicine. We welcome talent driven by innovation and committed to improving global health. This is an enterprise leadership opportunity to set the strategic direction for global clinical trial operations across Moderna’s clinical development portfolio, spanning Oncology, Therapeutics, Infectious Disease, and future therapeutic areas and modalities. You will lead the global organization responsible for translating development strategy into high-quality, executable clinical plans, ensuring studies are delivered with rigor across quality, ethics, participant safety, compliance, timelines, budgets, resources, and external partnerships. Operating with strategic vision and hands-on operational depth, you will shape how Moderna plans and executes its clinical portfolio globally while building the organization, operating models, digital capabilities, and data-driven approaches needed to accelerate development and patient impact. Here’s What You’ll Do Set the strategic direction for global clinical trial operations across Moderna’s clinical development portfolio, ensuring Clinical Operations priorities remain aligned with enterprise, development, and therapeutic area objectives. Lead the global Clinical Operations organization accountable for the planning, execution, delivery, and reporting of clinical studies across all phases of development, maintaining the highest standards of quality, ethics, participant safety, regulatory compliance, operational discipline, budget accountability, and timeline performance. Lead, mentor, and develop a high-performing global Clinical Operations team, fostering a culture of accountability, collaboration, continuous improvement, ownership, operational excellence, and strong leadership at every level of the organization. Provide leadership and direction to portfolio and franchise leaders, Program Clinical Operations Leads (PCOLs), and study Clinical Operations Leads (COLs), enabling successful execution of global clinical studies in accordance with ICH-GCP, applicable regulations, and Moderna standards. Partner closely with Therapeutic Area Development Heads and functional line leaders to translate portfolio and development strategy into executable operational plans, resourcing models, study timelines, budget assumptions, and delivery priorities. Ensure the Clinical Operations portfolio is appropriately prioritized, resourced, and actively managed, deploying and reallocating resources in response to emerging clinical data, portfolio changes, development needs, and shifting business priorities. Manage Clinical Operations budgets and resources with strong financial and operational discipline, ensuring alignment with long-range planning, annual planning, and periodic budget review cycles. Drive operational excellence across the portfolio by identifying and implementing process improvements, best practices, data-driven planning approaches, performance metrics, and scalable operating models that improve predictability, quality, speed, and execution. Create opportunities for Clinical Operations leaders and teams to work closely with Generative AI, advanced analytics, automation, and other digital tools to strengthen scenario planning, portfolio insights, operational decision-making, productivity, and the speed at which teams can learn and act. Develop and maintain strong relationships with critical internal and external stakeholders, including regulatory authorities, investigators, strategic site networks, vendors, CRO partners, government or fun

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