Senior Advisor, Clinical Science (remote)

Eli Lilly2 Locationsremote$153k–$268kView the original posting at Eli Lilly ↗

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us. Organization and Position Overview Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa’s lead investigational candidate – cleminorexton (formerly ORX750) – is being developed for narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia. Centessa's OX2R agonist portfolio includes additional clinical and preclinical-stage assets with potential utility across a broader range of neurological, neurodegenerative, and neuropsychiatric conditions. Headquartered in Boston, Massachusetts, Centessa was recognized as a Great Place to Work® in 2026. We are seeking a Senior Advisor, Clinical Science to serve as the scientific partner to the study team and medical monitor in the execution and interpretation of primarily late-stage (Phase 2-3) clinical trials for our Orexin-targeted programs in sleep/wake indications . This individual will perform at the Associate Director level to bring clinical and scientific expertise to day-to-day study conduct, ensuring that studies are run in line with the protocol, compliant with internal processes, GCP/ICH and regulatory requirements, and in alignment with the broader clinical development strategy. Activities include, but are not limited to, protocol development; scientific leadership for study startup; trial execution; driving recruitment; study and data monitoring; and data analysis upon close out. This role will serve as a key cross-functional partner to Clinical Operations, Translational Science, Regulatory Affairs, Biostatistics, and Safety/Pharmacovigilance. This role will report to the Executive Director, Clinical Development. Responsibilities Serve as clinical scientist on one or more late-stage (Phase 2-3) global clinical trials for Orexin-targeted programs in sleep/wake indications. Support the creation of and/or review of clinical slides for internal and external meetings (e.g. Investigator Meetings, SIVs, IDMCs, Advisory Boards, etc.) Assist in authoring key clinical study documents, including Protocols, Clinical Study Reports, Investigator Brochures, Development Safety Update Reports etc. Serve as study scientific expert from study start-up through clinical study report completion, including CRF design, enrollment monitoring, and patient profile review. Primary liaison for internal Clinical Operations for site selection, site start-up activities, study management and closeout activities, etc. undefined Primary point of contact for clinical inquiries from sites, CRO and site monitors, and health authority responses; answer or triage questions as appropriate integration of clinical/regulatory strategy into global product development strategy. Perform ongoing clinical data review to monitor safety, data integrity, protocol compliance, and study performance throughout trial execution. Serve as a core scientific leader on cross-functional program/study teams, partnering closely with Clinical Operations, Regulatory Affairs, Biostatistics, and Safety/Pharmacovigilance. Drive alignment and execution across functions to support high-quality, timely study delivery. Proactively identify and address scientific, operational, and strategic risks and gap

The people who work here are one introduction away.

We show you who they are and write your first message — the insider list for this posting is filling in now. You have one introduction. The rest follows.

People at Eli Lilly you can reach out to

8 of 74 public LinkedIn profiles found in searches for Eli Lilly list Eli Lilly in their headline — those are the ones you can be confident work there. Pick who to reach out to — we'll draft your message; you make the contact. The rest, when shown, are marked Unverified.

Profiles are public pages as indexed by the search engine — we never log in to LinkedIn or copy private data, and anyone can ask to be removed. Ask to be removed →

Start the conversation More CRA jobs

Remote CRA jobs →Entry level CRA jobs →Senior CRA jobs →All Eli Lilly jobs →