Associate Director, Clinical Drug Safety

Eli Lilly2 Locationsonsite$117k–$189kView the original posting at Eli Lilly ↗

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us. Organization and Position Overview Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa’s lead investigational candidate – cleminorexton (formerly ORX750) – is being developed for narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia. Centessa's OX2R agonist portfolio includes additional clinical and preclinical-stage assets with potential utility across a broader range of neurological, neurodegenerative, and neuropsychiatric conditions. Headquartered in Boston, Massachusetts, Centessa was recognized as a Great Place to Work® in 2026. We are seeking an Associate Director, Clinical Drug Safety, to support pharmacovigilance activities across Centessa’s clinical-stage development programs. Reporting to Centessa’s Executive Director - Safety Science, this role will contribute to the review and analysis of safety data to support ongoing safety surveillance activities such as signal management, serve as key analytic and safety support for regulatory compliance/program execution and support overseeing aggregate reports production and literature review. The Associate Director will work closely with cross-functional partners and external vendors to ensure high-quality safety deliverables and maintain inspection-ready processes in a fast-paced, development-focused environment. Responsibilities Signal Detection and Management Support the implementation of signal identification and management strategy, coordinating discussions within the Drug Safety team and cross‑functional partners. Drive ongoing safety surveillance activities by analyzing aggregate safety data, identifying emerging safety signals, and contributing to risk–benefit assessments for investigational products. Review adverse event data and other safety-related data for signal detection activities. Oversee literature surveillance to identify new or evolving safety information, interpret clinical relevance, and communicate findings as appropriate. Responsible for signaling review and the coordination of signal review activities with Drug Safety and cross-functional teams. Support in the preparation of safety governance slides and documentation of meeting minutes. Aggregate reports support Provide scientific input into the preparation and review of aggregate reports such as DSURs and line listings. Oversee DSUR strategy, preparation and adherence to timelines with key cross-functional partners and vendor. Demonstrate effective skills with cross-functional partners to ensure that safety data authorship for aggregate reports such as DSUR are high quality. Safety Scientist support during all phases of product development Provide scientific input into the preparation and review of safety‑related sections of protocols, Investigator’s Brochures, and regulatory submissions. Serve as the lead drug safety representative on cross‑functional study teams and in collaboration with senior Drug Safety team, shaping safety strategy, influencing program decision‑making, and advising on safety issue management. Maintain expert‑level knowledge of therapeutic areas and evolving global drug safety regulations, guidelines and best practices, and ap

The people who work here are one introduction away.

We show you who they are and write your first message — the insider list for this posting is filling in now. You have one introduction. The rest follows.

People at Eli Lilly you can reach out to

8 of 74 public LinkedIn profiles found in searches for Eli Lilly list Eli Lilly in their headline — those are the ones you can be confident work there. Pick who to reach out to — we'll draft your message; you make the contact. The rest, when shown, are marked Unverified.

Profiles are public pages as indexed by the search engine — we never log in to LinkedIn or copy private data, and anyone can ask to be removed. Ask to be removed →

Start the conversation More Pharmacovigilance jobs